Ravi,
I hope you enjoyed the OTM SIG conference and apologize for the delay in responding -- getting ready for the Conference took a lot of my time
There is a major Freight Forwarder who is using OTM and they are based in Philadelphia. In fact, the current features in GC3 / OTM were developed specifically around their needs. My partner (Samuel Levin) helped them architect their OTM solution and worked with them for a couple of years. I'm also aware of a couple smaller freight forwarders who are considering OTM.
If you have specific questions, please feel free to post them under the "Freight Forwarding" section and we'll do our best to help you out.
Thanks!
--Chris